Against All Odds (2006) was a professional wrestling pay-per-view (PPV) event produced by Total Nonstop Action Wrestling (TNA), which took place on February 12, 2006 at the TNA Impact! Zone in Orlando, Florida. It was the second event under the Against All Odds chronology. Eight matches were featured on the event's card.

Jeffrey Jarrett
Jeff Jarrett

Jason Reso
Christian Cage

Mark LoMonaco
Brother Ray

Devon Hughes
Brother Devon

Robert Roode Jr.
Bobby Roode

Jeremy Fritz
Eric Young

Nuufolau Joel Seanoa
Samoa Joe

Allen Jones
AJ Styles

Daniel Covell
Christopher Daniels

Terry Gerin
Rhino

Chris Parks
Abyss

James Cox
"Cowboy" James Storm

Chris Harris
"Wildcat" Chris Harris

Josh Harter
Chris Sabin

Retesh Bhalla
Sonjay Dutt
