In 1896 the Berlin noble doctor Dr. Wilhelm Holtfreter takes over his well-to-do wife Mathilde and takes over the country doctor's office in the Prussian district of Westprignitz from the late Dr. Tochtenhagen. His decision was met with incomprehension everywhere.

Kurt Böwe
Dr. Holtfreter

Barbara Dittus
Mathilde Holtfreter

Gudrun Ritter
Helene Tochtenhagen

Reimar Johannes Baur
Aurelius Weinreich

Arno Wyzniewski

Dagmar Manzel
Harriet von Vietz

Peter Bause

Jenny Gröllmann
Leontine Bachofen

Ulrich Mühe
Raoul Fürstenau

Jaecki Schwarz
Dr. Willibald Köhn

Ulrike Mai

Carl Heinz Choynski

Ingrid Rentsch
Gertrud von Altenow

Werner Dissel
Kutscher Pankoke

Rolf Ludwig