The story chronicles the first recorded meeting in the late 16th Century between British explorers-settlers and Native Americans in what is now North Carolina, and the conflicts that ensued between the two diverse cultures before this early settlement mysteriously vanished.

Victor Garber
John White

Paul Guilfoyle

Patrick Kilpatrick
Amadas

Joseph Runningfox
Wanchese

Will Sampson
Wingina

Adrian Sparks
Ralph Lane
Tino Juarez
Manteo
Eddie Benton-Banai
Tirchtough
Sherry Blakey-Banai
Ascopo

Victoria Racimo
Appomosiscut
Ralph Brannen
Cossine

J. Kenneth Campbell
Walter Ralegh
Andrew Davis
Harriot

James Eckhouse

Giancarlo Esposito
Simon Fernandes